Pakistan’s ex-military ruler Pervez Musharraf dies of amyloidosis; know more about the rare condition

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Pakistan’s ex-military ruler Pervez Musharraf dies of amyloidosis; know more about the rare condition

Immediately upon Musharraf’s passing, Inter-Services Public Relations (ISPR), the Pakistani military’s media wing, released a statement praying to Allah  “bless the departed soul and give strength to the bereaved family.”

General (ret.) Pervez Musharraf, the former military ruler of Pakistan, passed away on Sunday in Dubai following a prolonged illness. The 79-year-old who planned the Kargil War in 1999 had amyloidosis, a rare condition brought on by the accumulation of an abnormal protein called amyloid in organs and tissues all over the body, according to his family, PTI reported. Musharraf passed away in a hospital in Dubai.

He has been receiving treatment at the American Hospital Dubai. He had been living in Dubai since 2016. The chairman of the Joint Chiefs of Staff Committee, General Sahir Shamshad, and all of the service chiefs expressed their deepest sympathies, according to a statement released by the Inter-Services Public Relations (ISPR), the media arm of the Pakistani military, shortly after Musharraf’s passing.

The message read, “May Allah bless the departed soul and provide courage to the bereaved family.”

What is the condition all about?

The illness has the potential to result in organ failure and death, according to Dr. Atul Ingale, Consultant Nephrologist and Transplant Physician, Director, Department of Nephrology, Fortis Hiranandani Hospital, Vashi.

It is categorized as a rare disease by the National Institutes of Health because, according to a National Center for Biotechnology Information study, it affects fewer than 2,00000 people in the United States.

According to Dr. Subhendu Mohanty, an interventional cardiologist at Sharda Hospital in Noida, amyloidosis affects various organs including the kidney, heart, occasionally the intestines, liver, etc. “Symptoms are organ-specific. They may exhibit a wide range of symptoms, including those of liver, heart, or renal failure. a very broad spectrum of symptoms. Since it is a rare sickness, it is difficult to identify symptoms. Strong clinical judgment is necessary, according to Dr. Mohanty.

How is it diagnosed? What causes it?

According to Dr. Ingale, amyloidosis is caused by the buildup of pathogenic amyloids (a form of protein), the majority of which are aggregates of misfolded proteins, in a range of tissues. It is difficult to detect and can cause a protracted demise, according to Dr. Ravi Shekhar Jha, director and head of pulmonology at Fortis Hospitals in Faridabad.

The unfortunate thing is that there is no known cure for the illness, Dr. Jha informed. It can be a symptom of another illness. In the same way, some people with bronchiectasis may also develop amyloidosis, and ultimately, they will die from amyloidosis rather than bronchiectasis. The area where this aberrant protein is deposited is gradually being destroyed.

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